有两种方法：

一、在server段写上2个Listen就可以了.

listen 192.168.0.123:8080;
listen 192.168.0.123:8089;
如上,就可以同时监听2个端口了.

二、在 nginx.conf 中配置多个个server即可

user nginx nginx;worker_processes  1;worker_rlimit_nofile 65535;events {    worker_connections  4000;
}http {    include       mime.types;    default_type  application/octet-stream;    autoindex off;    log_format  main  '$remote_addr - $remote_user [$time_local] "$request" '
                      '$status $body_bytes_sent "$http_referer" '
                      '"$http_user_agent" "$http_x_forwarded_for"'
                       '$upstream_addr $upstream_response_time $request_time ';    access_log  logs/nginx/access.log main;    sendfile        on;    keepalive_timeout  65;        upstream localhost {        server 127.0.0.1:80800 max_fails=7 fail_timeout=7s;
    } 

    server {        listen       8080;        server_name  localhost;                large_client_header_buffers 4 128k;        client_max_body_size 300m;        client_body_buffer_size 128k;        proxy_connect_timeout 600;        proxy_read_timeout 600;        proxy_send_timeout 600;        proxy_buffer_size 64k;        proxy_buffers   4 32k;        proxy_busy_buffers_size 64k;        proxy_temp_file_write_size 64k;#设定查看Nginx状态的地址
        location /nginxstatus{            stub_status on;            access_log on;            auth_basic "nginxstatus";            auth_basic_user_file htpasswd;
    }#ftpweb
         location /ftpweb {           index  index.html index.htm index.jsp;           proxy_pass  http://www.landui.com:9081/ftpweb;           proxy_set_header X-Real-IP $remote_addr;           proxy_set_header Host $host:$server_port;
        }#Zabbixweb
         location /webzabbix/ {           index  index.html index.htm index.jsp;           proxy_pass  http://www.landui.com/zabbix/;           proxy_set_header X-Real-IP $remote_addr;           proxy_set_header Host $host:$server_port;
        }        error_page   500 502 503 504  /50x.html;        location = /50x.html {            root   html;
        }

    }    server {        listen       8089;        server_name  localhost;        large_client_header_buffers 4 128k;        client_max_body_size 300m;        client_body_buffer_size 128k;        proxy_connect_timeout 600;        proxy_read_timeout 600;        proxy_send_timeout 600;        proxy_buffer_size 64k;        proxy_buffers   4 32k;        proxy_busy_buffers_size 64k;        proxy_temp_file_write_size 64k;#开放8089接口地址
         location /interserver {           index  index.html index.htm index.jsp;           proxy_pass  http://www.landui.com:8812/interserver/;           proxy_set_header X-Real-IP $remote_addr;           proxy_set_header Host $host:$server_port;
        }

    }

}

这样就就可以一个nginx服务访问8080和8089两个端口到不同服务的了